The Bipolar Spectrum: The Different Types of Bipolar Disorder

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Bipolar disorder is a serious clinical entity that often generates bewilderment and fear. In addition, there are up to nine different forms of bipolar disorder. In this article, we’re going to explain the different types. Bipolar disorder is a serious and disabling clinical entity . Its onset usually occurs […]

Sleep spindles in people with schizophrenia, schizoaffective disorders or bipolar disorders: a pilot study in a general population-based cohort

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Abstract Background Sleep spindles have been involved in sleep stabilization and sleep-related memory mechanisms and their deficit emerged as possible biomarker in schizophrenia. However, whether this sleep phenotype is also present in other disorders that share psychotic symptoms remains unclear. To address this gap, we assessed sleep spindles in […]

Link Between Genetics and Neuropsychiatric Disorders Confirmed

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Summary: 1% of patients registered in a health initiative carry at least one rare gene variant linked to an increased risk of a neuropsychiatric disorder such as schizophrenia or bipolar disorder. One-third of those with a variant had been diagnosed with a mental health disorder. Source: Geisinger Health System […]

New study reveals differences in diagnosis of psychiatric disorders between geographies

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image: The red numbers indicate the genetic correlation between bipolar disorders (BD) subtypes I and II, schizophrenia (SCZ), and major depressive disorder (MDD). The top triangle corresponds to the results obtained for an East Asian (EAS) population, whereas the bottom triangle corresponds to the results derived from a European […]

New study reveals differences in diagnosis of psychiatric disorders between Eastern and Western countries

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Genetic correlation between subtypes of bipolar disorder (BD1/BD2) and schizophrenia/major depressive disorder (SCZ/MDD) in East Asian and European populations. In the correlation matrix, the upper (black) and lower (red) triangles represent East Asian and European samples, respectively. The numbers correspond to scores of genetic correlation (r g ). The […]

Acid produced by the brain could drive disease-related psychosis

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MRI brain scans from a person with Alzheimer’s disease A chemical called kynurenic acid may play a role in diseases characterised by cognitive impairments or psychosis, including schizophrenia , Alzheimer’s disease and bipolar disorder. Newly developed drugs that reduce this acid in the brain show promise in reducing symptoms […]

Antidepressants that increase mitochondrial energetics may elevate risk of treatment-emergent mania

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Abstract Preclinical evidence suggests that antidepressants (ADs) may differentially influence mitochondrial energetics. This study was conducted to investigate the relationship between mitochondrial function and illness vulnerability in bipolar disorder (BD), specifically risk of treatment-emergent mania (TEM). Participants with BD already clinically phenotyped as TEM+ ( n = 176) or […]

Managing Agitation in Bipolar Disorder, Schizophrenia

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During the 2022 Neuroscience Education Institute (NEI) Congress , Leslie Citrome, MD, MPH, clinical professor of psychiatry and behavioral sciences at New York Medical College in Valhalla, discussed the current treatment paradigm for agitation in individuals with schizophrenia and bipolar disorder, as well as novel and investigational treatment options […]

Bipolar Disorder Treatment Market 2022: Rising With Immense Development Trends Across The Globe By 2028 | Takeda Pharmaceutical Company Limited, Pfizer, Inc., Allergan plc

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Bipolar Disorder Treatment Market Size Projections : The global bipolar disorder treatment market size is estimated to be valued at US$ 7,288.3 million in 2021 and is expected to exhibit a CAGR of 5.2% over the forecast period (2022-2028). Manic illness, another name for bipolar disease, is a brain […]