Blood Brain Barrier Query Results
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Denali unveils new way of crossing blood brain barrier as the big neuroscience bets enter its clinical years
Click here to view original web page at endpts.com Five years ago, as much of pharma began leaving neuroscience, three big-name scientists from Genentech and some A-list investors, including ARCH and Flagship, made a $217 million bet that new genetic insights and a reliance on biomarkers could bring them success. They called it Denali Therapeutics. … Continue reading “Denali unveils new way of crossing blood brain barrier as the big neuroscience bets enter its clinical years”
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Denali Therapeutics unveils blood-brain barrier delivery system
Click here to view original web page at cen.acs.org Case Hogan, who has Hunter syndrome, is in a clinical study of an intrathecally-delivered enzyme therapy. Researchers have long been vexed by the brain’s ability to shut out drugs. Now, Denali Therapeutics is offering evidence in mice and monkeys that a new drug delivery system can … Continue reading “Denali Therapeutics unveils blood-brain barrier delivery system”
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Focused Ultrasound Could Let Drugs Bypass the Blood-Brain Barrier
Click here to view original web page at www.technologynetworks.com University of Virginia researchers are pioneering the use of focused ultrasound to defy the brain’s protective barrier so that doctors could, at last, deliver many treatments directly into the brain to battle neurological diseases. The approach, the researchers hope, could revolutionize treatment for conditions from Alzheimer’s … Continue reading “Focused Ultrasound Could Let Drugs Bypass the Blood-Brain Barrier”
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Nanoparticle Drug Delivery Technology Can Cross the Blood-Brain Barrier
Click here to view original web page at www.technologynetworks.com Delivery of pharmaceuticals by nanocarrier through the blood-brain barrier can be done using the newly discovered cyclic peptide. Credit: Professor Sumio Ohtsuki A Japanese research team has developed a cyclic peptide (a chain of amino acids bonded circularly) that enhances blood-brain barrier (BBB) penetration. By attaching … Continue reading “Nanoparticle Drug Delivery Technology Can Cross the Blood-Brain Barrier”
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WVU Rockefeller Neuroscience Institute first in the world to open hippocampal blood brain barrier in Alzheimer’s patients
Click here to view original web page at wvumedicine.org New study published in PNAS with Weill Cornell validates successful use of focused ultrasound to treat six patients MORGANTOWN, W.Va. – The West Virginia University Rockefeller Neuroscience Institute today announced a new study published in partnership with Weill Cornell Medical Center that demonstrates the successful opening … Continue reading “WVU Rockefeller Neuroscience Institute first in the world to open hippocampal blood brain barrier in Alzheimer’s patients”
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The Blood-Brain Barrier: Now on a Chip
Click here to view original web page at www.technologynetworks.com A scrupulous gatekeeper stands between the brain and its circulatory system to let in the good and keep out the bad, but this porter, called the blood-brain barrier, also blocks trial drugs to treat diseases like Alzheimer’s or cancer from getting into the brain. Now a … Continue reading “The Blood-Brain Barrier: Now on a Chip”