The Neuronal Basis of Impaired Consciousness in Absence Epilepsy

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Summary: During absence seizures, most neurons showed decreased activity. This, researchers say, explains the decrease in brain function and impaired consciousness during an absence epilepsy seizure. Source: Yale Imagine slipping in and out of consciousness hundreds of times per day, staying awake the whole time but having no sense […]

Absence of Biomarker Profiles Typical of Alzheimer’s Disease

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Summary: Findings highlight the need to continue developing new disease-modifying treatments with different mechanisms of action for patients with Alzheimer’s disease. Source: Karolinska Institute A new study from Karolinska Institutet and the Karolinska University Hospital indicates that only a rather small proportion of individuals attending a specialized memory clinic […]

Absence of Biomarker Profiles Typical of Alzheimer’s Disease

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Summary: Findings highlight the need to continue developing new disease-modifying treatments with different mechanisms of action for patients with Alzheimer’s disease. Source: Karolinska Institute A new study from Karolinska Institutet and the Karolinska University Hospital indicates that only a rather small proportion of individuals attending a specialized memory clinic […]

How Does the Cerebellum Affect Absence Seizures?

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Stimulation of certain cerebellar areas could help combat absence seizures. However, what happens at the cellular and molecular level in the brain in this form of epilepsy and how exactly stimulation has an effect is not yet understood in detail. Researchers at Ruhr-Universität Bochum (RUB) have gained new insights […]

Autism, ADHD and School Absence Are Risk Factors for Self-Harm

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Summary: The risk of self-harm presenting to emergency rooms is three times higher for boys with ASD compared to those not on the autism spectrum. Additionally, researchers found a four-fold increase in self-harm behaviors for both males and females with ADHD. Children with less than 80% school attendance also […]

Caltech Scientists Explore Link Between Germs and Anti-Social Behavior

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This diagram illustrates the cascade of changes occurring in the mouse body and brain in the absence of a gut microbiome. Lack of gut microbes leads the adrenal gland to produce more corticosterone, a stress hormone, which then influences a neural circuit controlling social behavior in the brain, making […]

Full-Genome CRISPR Screen Reveals Surprsing Ways Neurons Survive Oxidative Stress

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Super-resolution microscopy of a neuron shows the accumulation of lipids within lysosomes that occurs when the gene for prosaposin is suppressed. Image credit: Kampmann Lab When a single gene in a cell is turned on or off, its resulting presence or absence can affect the function and survival of […]

Loneliness predicts development of type 2 diabetes

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Published in the journal Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]), the study shows that it is the absence of quality connections with people and not the lack of contact that predicts the onset of type 2 diabetes, suggesting that helping people form […]

Gene absence linked to male neural development

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Credit: CC0 Public Domain Research conducted by the University of Valencia (UV) and the Jaume I University of Castellón (UJI), among other institutions, has found alterations to the structure of the brain’s nonapeptidergic systems, social behavior and the production of pheromones, traits that reveal sexual dimorphism, in male mice […]

Brain Connectivity Changes Linked to Auditory Hallucinations

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Credit: rawpixel Auditory hallucinations, a phenomenon in which people hear voices or other sounds in the absence of external stimuli, are a feature of schizophrenia and some other neuropsychiatric disorders. How they arise in the brain has been unclear, but new research indicates that altered brain connectivity between sensory […]